Endocrine Abstracts

Background: The alpha2B adrenoceptor gene, a candidate gene for essential hypertension, harbours a functional insertion/deletion (I/D) polymorphism of three glutamate residues.Objectives: The aim of this study was to investigate whether the presence of the D allele is associated with hypertension in Greek patients with type 2 diabetes mellitus (T2DM).Patients-methods: One hundred and twenty-nine hypertensive (64 male, mean age: 66....

Objective: To investigate the potential association between serum inflammatory cytokine levels and thyroxine replacement dose in patients with Hashimoto disease.Patients and methods: The study included 40 patients (12 men) with a mean age of 56.52±6.12 years who had hypothyroidism due to Hashimoto disease. Serum Interleukin-1b (IL-1b), Tumour Necrosis Factor-alpha (TNF-alpha) and Interleukin-6 (IL-6) levels, as well as TSH, fT3 and fT<sub...